Contact details
Dr Anna M Randi
Reader in Cardiovascular Medicine
National Heart & Lung Institute
Tel: +44 (0)20 7594 2721
Email:
Dr Anna M. Randi
Anna Randi is Reader in Cardiovascular Medicine at the National Heart and Lung Institute.
Dr. Anna Randi graduated from medical school at the University of Milan (Italy) and she went on to specialise in Haematology. She obtained her PhD with Prof P.M. Mannucci, on the molecular basis of von Willebrand Disease. As part of her scientific training, Dr Randi spent 3 years at Washington University, Howard Hughes Medical Institute, St. Louis, in Dr. Evan Sadler’s laboratory.
She then moved to the UK to take up a postdoctoral position for 2 years at Cancer Research UK, in Dr. Nancy Hogg’s laboratory. Here she was recruited by GlaxoSmithkline, where she was first Group Leader in Vascular Diseases and then Head of Translational Medicine in the Inflammation area. Whilst at GSK, Dr. Randi also held an honorary contract with Imperial College, and collaborated with Prof. Haskard and the British Heart Foundation on gene expression profiling of cardiovascular diseases.
Dr. Randi moved to Imperial in 2003 as a Clinical Senior Lecturer in NHLI and was promoted to her current position in 2010.
Her research interests focus on vascular biology, in particular the role of endothelial cells in maintaining vascular health, and on human endothelial progenitor cells and their potential as translational tools in vascular diseases.
Selected Publications
Journals
- Dryden NH; Sperone A; Martin-Almedina S; Hannah RL; Birdsey GM; Khan ST; Layhadi JA; Mason JC; et alHaskard DO; Göttgens B; Randi AM. (6 Apr 2012). The Transcription Factor Erg Controls Endothelial Cell Quiescence by Repressing Activity of Nuclear Factor (NF)-κB p65. J Biol Chem. 287:12331-12342. DOI.
- Birdsey GM; Dryden NH; Shah AV; Hannah R; Hall MD; Haskard DO; Parsons M; Mason JC; et alZvelebil M; Gottgens B; Ridley AJ; Randi AM. (19 Jan 2012). The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis. Blood. 119:894-903. DOI.
- Starke RD; Paschalaki KE; Ferraro F; Dryden NH; McKinnon TA; Sutton RE; Payne EM; Haskard DO; et alHughes AD; Cutler DF; Laffan MA; Randi AM. (Oct 2011). 39 Blood-derived endothelial progenitor cells from Von Willebrand's disease patients demonstrate that Von Willebrand factor regulates angiogenesis. Heart. 97:e7. DOI.
- Starke RD; Ferraro F; Paschalaki KE; Dryden NH; McKinnon TA; Sutton RE; Payne EM; Haskard DO; et alHughes AD; Cutler DF; Laffan MA; Randi AM. (20 Jan 2011). Endothelial von Willebrand factor regulates angiogenesis. Blood. 117:1071-1080. DOI.
- Sperone A; Dryden NH; Birdsey GM; Madden L; Johns M; Evans PC; Mason JC; Haskard DO; et alBoyle JJ; Paleolog EM; Randi AM. (Jan 2011). The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells. Arterioscler Thromb Vasc Biol. 31:142-150. DOI.
