Contact details
Dr Cesare M Terracciano
Reader in Cardiac Electrophysiology
National Heart & Lung Institute
Tel: +44 (0)20 7594 2735
Email:
Dr Cesare M Terracciano
Dr Cesare Terracciano is Reader in Cardiac Electrophysiology and the head of the Laboratory of Cellular Electrophysiology at the Harefield Heart Science Centre. He graduated in Medicine at the Universita' La Sapienza of Roma, Italy, in 1989 and qualified in Cardiology in the same medical school in 1993. He obtained his PhD in Physiology in 1995 on "Excitation-Contraction Coupling and intracellular acidosis in the heart" at the National Heart & Lung Institute, London. In 1998 he received a Wellcome Trust Career Development Fellowship and his work is now funded by the British Heart Foundation, the Wellcome Trust and the Magdi Yacoub Institute.
Dr Terracciano's main interest is the elecrophysiology of the diseased myocardium and the consequences of treatment on the contractile and electrical properties of the heart. His research fosuses in particular on the mechanisms of myocardial regeneration following mechanical devices or stem and gene therapy, and the cellular and molecular mechanisms of arrhythmias.
See Dr Terracciano's profile in Circulation - European Perspectives - 22 June 2010
Selected Publications
Journals
- Stagg MA; Carter E; Shorabi N; Siedlecka U; Soppa G; Mead F; Mohandas N; Taylor-Harris P; et alBaines A; Bennett P; Yacoub MH; Pinder J; Terracciano CM. (10 Oct 2008). Cytoskeletal protein 4.1R affects repolarization and regulates calcium handling in the heart. Circulation Research. 103:855-863. DOI.
- Ibrahim M; Terracciano CM; Yacoub MH. (Nov 2011). Bridge to recovery: what remains to be discovered?. Cardiol Clin. 29:531-547. DOI.
- Ibrahim M; Gorelik J; Yacoub MH; Terracciano CM. (22 Sep 2011). The structure and function of cardiac t-tubules in health and disease. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 278:2714-2723. DOI.
- Camelliti P; Al-Saud SA; Smolenski RT; Al-Ayoubi S; Bussek A; Wettwer E; Banner NR; Bowles CT; et alYacoub MH; Terracciano CM. (Sep 2011). Adult human heart slices are a multicellular system suitable for electrophysiological and pharmacological studies. J Mol Cell Cardiol. 51:390-398. DOI.
- Ibrahim M; Al Masri A; Navaratnarajah M; Siedlecka U; Soppa GK; Moshkov A; Al-Saud SA; Gorelik J; et alYacoub MH; Terracciano CM. (Sep 2010). Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface. FASEB J. 24:3321-3329. DOI.
- Chambers JC; Zhao J; Terracciano CM; Bezzina CR; Zhang W; Kaba R; Navaratnarajah M; Lotlikar A; et alSehmi JS; Kooner MK; Deng G; Siedlecka U; Parasramka S; El-Hamamsy I; Wass MN; Dekker LR; de Jong JS; Sternberg MJ; McKenna W; Severs NJ; de Silva R; Wilde AA; Anand P; Yacoub M; Scott J; Elliott P; Wood JN; Kooner JS. (Feb 2010). Genetic variation in SCN10A influences cardiac conduction. Nat Genet. 42:149-152. DOI.
- Terracciano CM; Miller LW; Yacoub MH. (2010). Contemporary use of ventricular assist devices. Annu Rev Med. 61:255-270. DOI.
- Lee J; Stagg MA; Fukushima S; Soppa GK; Siedlecka U; Youssef SJ; Suzuki K; Yacoub MH; et alTerracciano CM. (Apr 2009). Adult progenitor cell transplantation influences contractile performance and calcium handling of recipient cardiomyocytes. Am J Physiol Heart Circ Physiol. 296:H927-H936. DOI.
- Soppa GK; Lee J; Stagg MA; Felkin LE; Barton PJ; Siedlecka U; Youssef S; Yacoub MH; et alTerracciano CM. (1 Mar 2008). Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure. Cardiovasc Res. 77:695-706. DOI.
- Terracciano CM; Hardy J; Birks EJ; Khaghani A; Banner NR; Yacoub MH. (18 May 2004). Clinical recovery from end-stage heart failure using left-ventricular assist device and pharmacological therapy correlates with increased sarcoplasmic reticulum calcium content but not with regression of cellular hypertrophy. Circulation. 109:2263-2265. DOI.
