Dr Graham S Cooke

Graham Cooke is a clinician scientist based within the Division of Infectious Diseases at the Wright-Fleming Institute. He trained in General Medicine and Infectious Diseases, working in Oxford, London and South Africa. His doctoral research focussed on human genetics of tuberculosis, HIV and malaria, using genome wide approaches to identify novel targets for intervention that form part of his current research activity. From 2006-2008 he was based at the Africa Centre for Health and Population Studies in KwaZulu-Natal investigating the clinical and public health aspects of HIV/TB care and treatment and he remains a collaborator there.

His current work is focussed on HIV co-infection (including HIV/hepatitis and HIV/MDR-TB) with  a particular emphasis on diagnostics .

Research

1. HIV/TB

• Development and evaluation of point-of-care and near patient diagnostics (see project page)
• Advancing findings from human genome wide association studies to develop biomedical intervention strategies for tuberculosis  in the setting of HIV

2. HIV/Hepatology

• STOP-HCV consortium (steering group member)
• Delivery of HIV/HBV treatment in resource-poor settings (PROLIFICA project)
• HCV/HIV clinical studies 
• Intervention for non-cirrhotic portal hypertension

3. Other areas

• Communicable Disease Group Research Tissue Bank

Based at the St Mary’s Campus of Imperial College NHS Healthcare Trust covering co-infection  (HIV, tuberculosis and hepatitis) and  Infectious Diseases consultation services within St Mary’s Hospital. Clinical enquiries should be made to 0203 312 1926. 

Teaching

Co-founded new  BSc in Global Health which enrolled its first students in 2010

Funding sources

MRC, Royal Society, EU, Treatment Action Group, Médecins sans Frontières, WHO StopTB, BRC Imperial College