Contact details
Professor Jeremy K Nicholson FMedSci
Chair In Biological Chemistry, Head of Department
Department of Surgery & Cancer
Tel: +44 (0)20 7594 3195
Email:
Professor Jeremy K Nicholson
Research Interests:.
- Molecular physio-chemical processes in metabolism and medicine.
- Development of novel spectroscopic and chemometric tools for investigating human disease and toxicological mechanisms.
- Metabolism-driven top-down systems biology and modelling of complex system failure.
- Personalised healthcare through metabolic phenotyping.
- Surgical metabonomics, real-time diagnostics and integrative patient modelling.
Membership of societies
Fellow of the Academy of Medical Sciences
Fellow of the Institute of Biology
Fellow of the Royal College of Pathologists
Fellow of the Royal Society of Chemistry
Fellow of the British Toxicological Society
Selected Honours and Awards etc.:
Honorary Professor of Systems Biology, Shanghai Jiao Tong University;
Honorary Professor of Analytical Chemistry, Chinese Academy of Sciences, Dalian, China;
Honorary Professor of Chemistry, Tsinghua University, Beijing, China;
Honorary Professor of Medicine, Zhe Jaing University, Hongzhou, China;
Honorary Professor of Systems Biology Shanghai TCM University, China;
Honorary Professor of Biological Spectroscopy, State Key Laboratory of Magnetic Resonance and Molecular & Atomic Physics, Chinese Academy of Sciences, Wuhan, China;
Honorary Director of the Metabonomics Research Centre, Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China;
Honorary Director of Wuhan Magnetic Resonance Research Centre, Chinese Academy of Sciences, Dalian, China.
The Royal Society of Chemistry: 21st Silver Medal for Analytical Science (1992)
The Chromatographic Society: Jubilee Silver Medal (1994)
The Royal Society of Chemistry: 21st SAC Gold Medal for Analytical Chemistry (1997)
Pfizer Academic Innovation Award for Chemical and Medicinal Technology (2002)
The Royal Society of Chemistry: Silver Medal for Chemical Biology (2003)
Pfizer Global Chemistry Disciplinary Prize (2006)
The Royal Society of Chemistry (2007) - Theophilus Redwood Lecturer
The Royal Society of Chemistry (2008) – Interdisciplinary award
NIH: Stars in Cancer and Nutrition Distinguished Lecturer (2010)
Semmelweis – Budapest Prize (2010)
External Scientific Duties:
Consulting Editor: Journal of Proteome Research (ACS)
Associate Editor: Biomarkers (Taylor Francis Press)
Editorial Board: Molecular Systems Biology
Spin off company
Non-Executive (Founder) Director, Metabometrix UK Ltd.
Selected Publications
Journals
- Clayton TA; Baker D; Lindon JC; Everett JR; Nicholson JK. (25 Aug 2009). Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. P NATL ACAD SCI USA. 106:14728-14733. DOI.
- Nicholson JK; Lindon JC. (23 Oct 2008). Systems biology - Metabonomics. NATURE. 455:1054-1056. DOI.
- Holmes E; Loo RL; Stamler J; Bictash M; Yap IK; Chan Q; Ebbels T; De Iorio M; et alBrown IJ; Veselkov KA; Daviglus ML; Kesteloot H; Ueshima H; Zhao L; Nicholson JK; Elliott P. (15 May 2008). Human metabolic phenotype diversity and its association with diet and blood pressure. Nature. 453:396-400. DOI.
- Clayton TA; Lindon JC; Cloarec O; Antti H; Charuel C; Hanton G; Provost JP; Le Net JL; et alBaker D; Walley RJ; Everett JR; Nicholson JK. (20 Apr 2006). Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature. 440:1073-1077. DOI.
- Nicholson JK; Holmes E; Wilson ID. (May 2005). Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol. 3:431-438. DOI.
- Nicholson JK; Connelly J; Lindon JC; Holmes E. (Feb 2002). Metabonomics: a platform for studying drug toxicity and gene function. Nat Rev Drug Discov. 1:153-161. DOI.
