Sandrine Claus

PhD student

Supervision: 
Pr. JK Nicholson
Pr. E Holmes
Dr. S Kochhar (Nestlé Research Center, Lausanne, Switzerland)

Phone: 0207 5943 202
Email: s.claus05@imperial.ac.uk

Personal website: http://www.sandrine-claus.org

Research project

I am interested in the relationship between the host and its intestinal microbiota. In particular, I focus on the influence of the microbiota on liver metabolism and on the consequences of this interaction on the systemic metabolism of the host.

Communications

2008  

Oral and poster presentation at the joint Symposium for International Association on Gnotobiology & Society for Microbial Ecology and Disease congress in Stockholm:
Modulation of hepatic metabolism by gut microbiota

2007

Poster presented at the 4th Yakult International Symposium in Verona:
Role of gut microbiota on liver metabolism and cytochromes P450 activity

Oral presentation at the 4th Prebiotics, Probiotics & New Foods congress in Rome:
Metabonomic investigation into the influence of gut microbiota on metabolic phenotypes

2006 

Poster presented at the 2nd Annual Meeting of the Metabolomics Society in Boston in June: Multi-tissue metabolic phenotypes of germ-free mice

Publications

Eveillard A., Lasserre F., de Tayrac M., Polizzi A., Claus S., Canlet C., Mselli-Lakhal L., Gotardi G., Paris A., Guillou H., Martin P. G., Pineau T. Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach. 2009. Toxicol Appl Pharmacol [Epub ahead of print] 

Claus S. P., Tsang T. M., Wang Y., Cloarec O., Skordi E., Martin FP., Rezzi S., Ross A., Kochhar S., Holmes E. and Nicholson J. K. Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes. Molecular Systems Biology 4: 219 (2008)

Skordi E., Yap I. K. S., Claus S. P., Martin FP., Cloarec O., Lindberg J., Schuppe-Koistinen I., Holmes E. and Nicholson J. K. Analysis of time-related metabolic fluctuations induced by ethionine in the rat. J Proteome Res. (6) 4572-4581 (2007)