Prof Simon A McG Thom MD FRCP

Contact details

Professor Simon A Thom MD FRCP

Clinical Professor of Cardiovascular Pharmacology
National Heart & Lung Institute

Tel: +44 (0)20 7594 1101
Email: Email address for Professor Simon A Thom MD FRCP

Prof Simon A McG Thom MD FRCP

Simon Thom is Professor of Cardiovascular Medicine and Pharmacology at the National Heart and Lung Institute, Imperial College London.  He is a Consultant Physician at St Mary’s Hospital, Paddington and Co-director of the Peart-Rose Cardiovascular Disease Prevention Clinic based in the International Centre for Circulatory Health.  He is also co-director of the NW London Diabetes Research Network – part of the UK national Clinical Research Network.

He trained at St Mary’s Medical School and subsequently in Bath, Newcastle-upon-Tyne and London.  He is a Fellow of the Royal College of Physicians, holds an MD from the University of London and was recently a member of the Executive Committee of the British Hypertension Society and the national hypertension guidelines group.

His clinical interests include general medicine, hypertension, cardiovascular disease prevention and hypertensive complications in pregnancy.  Research interests include vascular pharmacology and physiology, structure and mechanics of the circulation and haemodynamics in relation to vascular disease.  He leads clinical trials of cardiovascular treatments – currently the multi-centered UMPIRE trial evaluating a “cardiovascular polypill” that includes collaborators and participants in India, Australia, the Netherlands, Ireland and UK. 

Research support comes from the British Heart Foundation, the Wellcome Trust, the European Commission, the Engineering & Physical Sciences Research Council (EPSRC) and the pharmaceutical industry.

 

 

Selected Publications


Journals

  • Manisty C; Mayet J; Tapp RJ; Parker KH; Sever P; Poulter NR; Thom SA; Hughes AD; et alASCOT Investigators. (29 Jun 2010). Wave reflection predicts cardiovascular events in hypertensive individuals independent of blood pressure and other cardiovascular risk factors: an ASCOT (Anglo-Scandinavian Cardiac Outcome Trial) substudy. J Am Coll Cardiol. 56:24-30. Author weblink DOI.
  • Thom S; Stettler C; Stanton A; Witt N; Tapp R; Chaturvedi N; Allemann S; Mayet J; et alSever P; Poulter N; O'Brien E; Hughes A. (1 Aug 2009). Differential Effects of Antihypertensive Treatment on the Retinal Microcirculation An Anglo-Scandinavian Cardiac Outcomes Trial Substudy. HYPERTENSION. 54:405-408. Author weblink DOI.
  • Torii R; Wood NB; Hadjiloizou N; Dowsey AW; Wright AR; Hughes AD; Davies J; Francis DP; et alMayet J; Yang GZ; Thom SA; Xu XY. (Mar 2009). Stress phase angle depicts differences in coronary artery hemodynamics due to changes in flow and geometry after percutaneous coronary intervention. Am J Physiol Heart Circ Physiol. 296:H765-H776. Author weblink DOI.
  • Williams B; Lacy PS; Cruickshank JK; Collier D; Hughes AD; Stanton A; Thom S; Thurston H; et alCAFE and ASCOT Investigators. (6 Jan 2009). Impact of statin therapy on central aortic pressures and hemodynamics: principal results of the Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) Study. Circulation. 119:53-61. Author weblink DOI.
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